Senolytics: 80 plus human trials, no approved drug, and mostly modest results

Longevity clinics sell senolytics for aging now. The evidence is not there yet. 80+ trials in 2026, zero FDA approvals. An NIA trial found limited bone benefit. Unity Biotech $UBX failed Phase 2 twice. One signal: 12% walk-distance gain in lung fibrosis. Source: NIA

Senolytics sold by longevity clinics as anti-aging. The science is more cautious. 80+ trials in 2026, zero FDA approvals. NIA trial found limited bone benefit. Unity $UBX failed Phase 2 twice. One signal: 12% walk gain in lung fibrosis. Early signals in kidney disease, frailty, osteoarthritis, Alzheimer's. Source: NIA